A super nice member!
We are using iTunes U as a foundation for our 1+1 MacBook Air/iPad program for middle and upper school students.
This cloud hosted service works is easy to manage using Safari using iTunes Course Manager, but this must be set up through your educational institution.
It is easy to build a course and syllabus and update information on the fly.
This program requires Lion/Safari to run the iTunes U Course Manager and an iPad to access the content.
The course management system works well, but lacks a social media/collaboration component.